Relevant publications of the European collaborating group:

Bulgaria

Tcheremenskaia O., G.Marucci, S. De Petris, F.M.Ruggeri, D. Dovecar, S. Ljubin Sternak, I. Matyasova, M.K. Dhimolea, Z.Mladenova, L. Fiore. Molecular epidemiology of rotavirus in Central and South-Eastern Europe. J Clin Microbiol 2007; 45: 2197-2204

Mladenova Z, Korsun N, Geonova T, Iturriza-Gómara M; Rotavirus Study Group. Molecular epidemiology of rotaviruses in Bulgaria: annual shift of the predominant genotype. Eur J Clin Microbiol Infect Dis. 2010 May;29(5):555-62. doi:

Mladenova Z, Iturriza-Gomara M, Esona MD, Gray J, Korsun N. Genetic characterization of Bulgarian rotavirus isolates and detection of rotavirus variants: challenges for the rotavirus vaccine program? J Med Virol. 2011 Feb;83(2):348-56. doi: 10.1002/jmv.21919.

Mladenova Z, Papp H, Lengyel G, Kisfali P, Steyer A, Steyer AF, Esona MD, Iturriza-Gómara M, Bányai K. Detection of rare reassortant G5P[6] rotavirus, Bulgaria. Infect Genet Evol. 2012 Dec;12(8):1676-84. doi: 10.1016/j.meegid.2012.07.002. Epub 2012 Jul 28

Mladenova Z, Nawaz S, Ganesh B, Iturriza-Gomara M. Increased detection of G3P[9] and G6P[9] rotavirus strains in hospitalized children with acute diarrhea in Bulgaria. Infect Genet Evol. 2015 Jan;29:118-26. doi: 10.1016/j.meegid.2014.11.011. Epub 2014 Nov 20.

Denmark

Fischer, T. K., Steinsland, H., Molbak, K., Ca, R., Gentsch, J. R., Valentiner-Branth, P., Aaby, P., Sommerfelt, H. 2000. Genotype profiles of rotavirus strains from children in a suburban community in Guinea-Bissau, Western Africa. J Clin Microbiol 38: 264-267.

Fischer, T. K. 2001. Incidence of hospitalizations due to rotavirus gastroenteritis in Denmark. Acta Paediatr 90: 1073-1075.

Fischer TK, Gentsch JR. Rotavirus typing methods and algorithms. Rev Med Virol. 2004; 14:71-82. Review.

Fischer TK, Page NA, Griffin DD, Eugen-Olsen J, Pedersen AG, Valentiner-Branth P, Molbak K, Sommerfelt H, Nielsen NM. Characterization of incompletely typed rotavirus strains from Guinea-Bissau: identification of G8 and G9 types and a high frequency of mixed infections. Virology. 2003;311:125-33.

Fischer TK. Epidemiological studies of rotavirus infection in Guinea-Bissau, West Africa. Dan Med Bull. 2003 May;50(2):103-17. Review. No abstract available. Erratum in: Dan Med Bull. 2003;50:282.

Fischer TK, Steinsland H, Valentiner-Branth P. Rotavirus particles can survive storage in ambient tropical temperatures for more than 2 months. J Clin Microbiol. 2002; 40: 4763-4.

Fischer TK, Valentiner-Branth P, Steinsland H, Perch M, Santos G, Aaby P,Molbak K, Sommerfelt H. Protective immunity after natural rotavirus infection: a community cohort study of newborn children in Guinea-Bissau, west Africa. J Infect Dis. 2002; 186:593-7.

Midgley S, Böttiger B, Jensen TG, Friis-Møller A, Person LK, Nielsen L, Barzinci S, Fischer TK. Human group A rotavirus infections in children in Denmark: detection of reassortant G9 strains and zoonotic P[14] strains. Infect Genet Evol J Mol Epidemiol Evol Genet Infect Dis. 2014 Oct;27:114–20.

Finland

Maunula L., L. Svensson, and C.H. von Bonsdorff. 1992. A family outbreak caused by group C rotavirus. Arch. Virol. 124:269-278.

Maunula, L. and C.-H. von Bonsdorff. 1995. Rotavirus serotypes and electropherotypes in Finland from 1986 to 1990. Arch. Virol. 140:877-890.

Maunula, L. and C.-H. von Bonsdorff. 1998. Short sequences define genetic lineages; Phylogenetic analysis of partial 4 and 9 sequences of group A rotaviruses. J. Gen. Virol. 79:321-332.

Vesikari T, Rautanen T, von Bonsdorff C-H. Rotavirus gastroenteritis in Finland:burden of disease and epidemiologic features. Acta Paediatrica 1998;Supplement.

Maunula, L. 2001. Molecular epidemiology of human rotaviruses – A study in genetic diversity. Thesis. University on Helsinki.

Maunula, L. and C.-H. von Bonsdorff. 2002. Frequent reassortments may explain the genetic heterogeneity of rotaviruses; Analysis of Finnish rotavirus strains. J.Virol. 76 :11793-11800.

France

Lorrot M, Bon F, Balay K, Marc E, Moulin F, Lebon P, Pothier P, Gendrel D. Rotavirussero/genotypes in France and worldwide. Arch Pediatr. 2005;12:838-840.

Chikhi-Brachet R, Bon F, Toubiana L, Pothier P, Nicolas JC, Flahault A, Kohli E. Virus diversity in a winter epidemic of acute diarrhea in France. J Clin Microbiol. 2002;40:4266-72.

Bon F, Fromantin C, Aho S, Pothier P, Kohli E. G and P genotyping of rotavirus strains circulating in france over a three-year period: detection of G9 and P[6] strains at low frequencies. The AZAY Group. J Clin Microbiol. 2000;38:1681-3.

Aho LS, Simon I, Bour JB, Morales-Gineste L, Pothier P, Gouyon JB. Epidemiology of viral nosocomial infections in pediatrics. Pathol Biol (Paris). 2000;48:885-92.

Bon F, Fascia P, Dauvergne M, Tenenbaum D, Planson H, Petion AM, Pothier P, Kohli E. Prevalence of group A rotavirus, human calicivirus, astrovirus, and adenovirus type 40 and 41 infections among children with acute gastroenteritis in Dijon, France. J Clin Microbiol. 1999;37:3055-8.

de Rougemont A, Kaplon J, Fremy C, Legrand-Guillien MC, Minoui-Tran A, Payan C, Vabret A, Mendes-Martins L, Chouchane M, Maudinas R, Huet F, Dubos F, Hober D, Lazrek M, Bouquignaud C, Decoster A, Alain S, Languepin J, Gillet Y, Lina B, Mekki Y, Morfin-Sherpa F, Guigon A, Guinard J, Foulongne V, Rodiere M, Avettand-Fenoel V, Bonacorsi S, Garbarg-Chenon A, Gendrel D, Lebon P, Lorrot M, Mariani P, Meritet JF, Schnuriger A, Agius G, Beby-Defaux A, Oriot D, Colimon R, Lagathu G, Mory O, Pillet S, Pozzetto B, Stephan JL, Aho S, Pothier P; French National Rotavirus Network. Clinical severity and molecular characteristics of circulating and emerging rotaviruses in young children attending hospital emergency departments in France. Clin Microbiol Infect Off Publ Eur Soc Clin Microbiol Infect Dis. 2016 Aug;22(8):737.e9-737.e15.

Hungary

Szücs G, Kende M, Uj M. 1987. Shift in genomic molecular patterns of human rotaviruses over an eighteen-month period in Hungary. Intervirology 28:110-113.

Szücs G, Matson DO, Új M, Kukán E, Mihály I, Jelenik Z, Estes MK. 1995. Group A rotavirus G type prevalence in two regions of Hungary. Arch Virol 140:1693-1703.

Szücs G, Új M, Mihály I, Deák J. 1999. Burden of human rotavirus-associated hospitalizations in three geographic regions of Hungary. Acta Paediatr (Suppl.) 88:61-65.

Bányai K, Gentsch JR, Glass RI, Szücs G. 2003. Detection of human rotavirus serotype G6 in Hungary. Epidemiol Infect 130:107-112.

Bányai K, Gentsch JR, Griffin DD, Holmes JL, Glass RI, Szücs G. 2003. Genetic variability among serotype G6 human rotaviruses: identification of a novel lineage isolated in Hungary J Med Virol , in press

Bányai K, Gentsch JR, Glass RI, Új M, Mihály I, Szücs G. Eight-year survey of human rotavirus strains demonstrates the circulation of unusual G and P types in Hungary. 2004. J Clin Microbiol; 42, 393-397.

Bányai K, Bogdán Á, Kisfali P, Molnár P, Mihály I, Martella V, Melegh B, Gentsch JR, Szücs G. 2007. Emergence of serotype G12 rotaviruses, Hungary. Emerging Infectious Diseases 13: 916-919

Mészner Z, Balogh A, Bányai K, Kovács J, Pazdiora P, Mrukowicz J, Molnár G, Tatochenko V, Avdicova M, Kraigher A. 2008. The clinical burden of rotavirus disease: Retrospective analysis of infant and childhood gastroenteritis in seven countries in Central and Eastern Europe. Pediatric Infectious Disease Journal 27: S33-S41.

Bányai K, Deak J, Gray J, Iturriza-Gómara M, Kovacs J, Konya J, Laszlo B,Martella V, Meszner Z, Mihály I, Molnar P, Nyul Z, Patri L, Schneider F, Toth A, Szucs G.2007. EuroRotaNet – European rotavirus strain surveillance network has been Established. Orv Hetil. Oct 28;148(43):2043-5.

László B, Nyúl Z, Kisfali P, Deák J, Kovács J, Kónya J, Mészner Z, Molnár P, Pátri L, Schneider F, Tóth A, Melegh B, Iturriza-Gomara M, Gray J, Martella V, Szucs G, Bányai K. First detection of P[6],G9 rotaviruses in Hungary–an imported strain from India? J Travel Med. 2009 Mar-Apr;16(2):141-3. doi: 10.1111/j.1708-8305.2008.00293.x.

László B, Kónya J, Dandár E, Deák J, Farkas Á, Gray J, Grósz G, Iturriza-Gomara M, Jakab F, Juhász Á, Kisfali P, Kovács J, Lengyel G, Martella V, Melegh B, Mészáros J, Molnár P, Nyúl Z, Papp H, Pátri L, Puskás E, Sántha I, Schneider F, Szomor K, Tóth A, Tóth E, Szűcs G, Bányai K. Surveillance of human rotaviruses in 2007-2011, Hungary: exploring the genetic relatedness between vaccine and field strains. J Clin Virol Off Publ Pan Am Soc Clin Virol. 2012 Oct;55(2):140–6.

Italy

Ianiro G, Delogu R, Bonomo P, Fiore L, Ruggeri FM; RotaNet-Italy Study Group. Molecular analysis of group A rotaviruses detected in adults and adolescents with severe acute gastroenteritis in Italy in 2012. J Med Virol. 2014 Jun;86(6):1073-82. doi: 10.1002/jmv.23871. Epub 2014 Jan 10

Ianiro G, Delogu R, Fiore L, Ruggeri FM; RotaNet-Italy Study Group. Evolution of human G4P[8] group A rotavirus strains circulating in Italy in 2013. Virus Res. 2015 Jun 2;204:68-73. doi: 10.1016/j.virusres.2015.04.007. Epub 2015 Apr 16.

Ianiro G, Delogu R, Fiore L, Monini M, Ruggeri FM; RotaNet–Italy Study Group. Group A rotavirus genotypes in hospital-acquired gastroenteritis in Italy, 2012-14. J Hosp Infect. 2017 Jul;96(3):262-267. doi: 10.1016/j.jhin.2017.04.004. Epub 2017 Apr 8.

Netherlands

Koopmans, M., and van Asperen, I. Epidemiology of rotavirus in The Netherlands. Acta Paediatrica 1999; 88 S426: 31-37.

Koopmans M., and Brown, D. Seasonality and diversity of rotaviruses across Europe. Acta Paediatrica. 1999; 88 S426:14-19.

Lodder, W.J., Vinje, J., van de Heide, R., Leenen, E.J.T.M., and Koopmans, M.P.G. Molecular detection of Norwalk-like caliciviruses and rotaviruses in sewage samples associated with outbreaks of gastroenteritis. Applied Environmental Microbiology. 1999; 65:5624-5627.

Wit MAS de, Koopmans MPG, Blij JF van der, Duynhoven YTPH van. Hospital admissions for rotavirus in the Netherlands. Clin Infect Dis. 2000; 3: 698-704.

de Wit, Koopmans, Kortbeek, van Leeuwen, Bartelds, and van Duynhoven. Gastroenteritis in sentinel practices in The Netherlands. Emerging infectious diseases Journal 2001;7:82-90.

de Wit MA, Kortbeek LM, Koopmans MP, de Jager CJ, Wannet WJ, Bartelds AI, van Duynhoven YT. A comparison of gastroenteritis in a general practice-based study and a community-based study. Epidemiol Infect 2001 ;127:389-97

Marc-Alain Widdowson, Gerard J.J. Doornum, Wim H.M.van der Poel, Annette S.de Boer, Ulrike Mahdi, Marion Koopmans. Protracted nosocomial outbreak of diarrhoea in neonates caused by newly emerging group A rotavirus genotype P[6]G9. Lancet, 2000;356:1161-2

de Wit M.A.S., Koopmans M.P.G., Kortbeek T., Leeuwen N. van, Vinjé J., Duynhoven Y. van. 2001. Etiology of gastroenteritis in Sentinel general practices in the Netherlands. Clin. Infect. Dis. 2001;33:280-8.

de Wit M.A., Koopmans M, Kortbeek, Leeuwen van, Bartelds, and Duynhoven Y. van. 2001 Sensor: a population-based cohort study on gastroenteritis in the Netherlands: incidence and etiology. Am. J. Public Health 154;7:666-674.

Widdowson MA, van Doornum GJ, van der Poel WH, de Boer AS, van de Heide R, Mahdi U, Haanen P, Kool JL, Koopmans M. An outbreak of diarrhea in a neonatal medium care unit caused by a novel strain of rotavirus: investigation using both epidemiologic and microbiological methods.Infect Control Hosp Epidemiol. 2002;23:665-70.

de Wit MA, Koopmans MP, van Duynhoven YT. Risk factors for norovirus, Sapporo-like virus, and group A rotavirus gastroenteritis. Emerg Infect Dis. 2003; 9:1563-70.

Boshuizen JA, Reimerink JH, Korteland-van Male AM, van Ham VJ, Koopmans MP, Buller HA, Dekker J, Einerhand AW. Changes in small intestinal homeostasis, morphology, and gene expression during rotavirus infection of infant mice. J Virol. 2003; 77:13005-16.

Slovenia

Steyer A, Poljsak-Prijatelj M, Luznik-Bufon T, Marcun-Varda N, Marin J. 2007. Rotavirus genotypes in Slovenia: unexpected detection of G8P[8] and G12P[8] genotypes. J Med Virol 79(5):626-632.

Fijan S, Steyer A, Poljsak-Prijatelj M, Cencic A, Sostar-Turk S, Koren S. 2007. Rotaviral RNA found on various surfaces in a hospital laundry. J. virol. methods, Available online 3 December 2007, http://dx.doi.org/10.1016/j.jviromet.2007.10.011

Steyer A, Poljsak-Prijatelj M, Barlic-Maganja D, Jamnikar U, Zimsek Mijovski J, Marin J. 2007. Molecular characterization of a new porcine rotavirus P genotype found in an asymptomatic pig in Slovenia. Virology 359(2):275-282.

Steyer A, Bajzelj M, Iturriza-Gómara M, Mladenova Z, Korsun N, Poljsak-Prijatelj M. Molecular analysis of human group A rotavirus G10P[14] genotype in Slovenia. J Clin Virol Off Publ Pan Am Soc Clin Virol. 2010 Oct;49(2):121–5.

Steyer A, Sagadin M, Kolenc M, Poljšak-Prijatelj M. Whole genome sequence analysis of bovine G6P[11] rotavirus strain found in a child with gastroenteritis. Infect Genet Evol J Mol Epidemiol Evol Genet Infect Dis. 2013 Jan;13:89–95.

Steyer A, Sagadin M, Kolenc M, Poljšak-Prijatelj M. Molecular characterization of rotavirus strains from pre- and post-vaccination periods in a country with low vaccination coverage: the case of Slovenia. Infect Genet Evol J Mol Epidemiol Evol Genet Infect Dis. 2014 Dec;28:413–25.

Spain

Buesa, F.J., M. Duato, C. Gimeno, J. García de Lomas. Sequential variation in genomic RNA patterns of human rotaviruses isolated from infantile gastroenteritis. Annales de l’Institute Pasteur; Virologie, 138: 307-314, 1987.

Buesa, J., Colomina, J., Raga, J., Villanueva, A., Prat, J. Evaluation of reverse transcription and polymerase chain reaction (RT/PCR) for the detection of rotaviruses: applications of the assay. Research in Virology, 147, 353-361, 1996.

Colomina, J., Gil, M.T., Codoñer, P., Buesa, J. Viral proteins VP2, VP6 and NSP2 are strongly precipitated by serum and fecal antibodies from children with rotavirus infection. Journal of Medical Virology, 56: 58-65, 1998.

Villanueva, A., MacCabe, A.P., Buesa, J., Ramón, D. Transient expression in Aspergillus nidulans and Aspergillus terreus of a cDNA encoding the major capsid antigen of rotavirus. Revista Iberoamericana de Micología, 16: 130-135, 1999.

Buesa, J., Raga J.V., Colomina, J. de Souza, C.O., Muñoz, C., Gil, M.T. Rotavirus-specific cytotoxic T lymphocyte recognize overlapping epitopes in the amino-terminal region of the VP7 glycoprotein. Virology, 257: 424-437, 1999.

Buesa, J., de Souza, C.O., Asensi, M., Martínez, C., Prat, J., Gil, M.T. VP7 and VP4 genotypes among rotavirus strains recovered from children with gastroenteritis over a 3-year period in Valencia, Spain. European Journal of Epidemiology, 16 (6): 501-506, 2000.

Gil, M.T., de Souza, C.O., Asensi, M., Buesa, J. Homotypic protection against rotavirus-induced diarrhea in infant mice breastfed by dams immunized with the recombinant VP8* subunit of the VP4 capsid protein. Viral Immunology, 13 (2): 187-200, 2000.

Gil, M.T., Pérez-Arellano, I., Buesa, J., Pérez-Martínez, G. Secretion of the rotavirus VP8* protein in Lactococcus lactis. FEMS Microbiology Letters, 203 (2): 269-274, 2001.

Ana García-Díaz, Pilar López-Andújar, Jesú Rodríguez Díaz, Rebeca Montava, Clara Torres Barceló, Juan M. Ribes, and Javier Buesa. Nasal immunization of mice with a rotavirus DNA vaccine that induces protective intestinal IgA antibodies. Vaccine, 23 (4): 489-498, 2004.

Rodríguez-Díaz, J., Monedero, V., Pérez-Martínez, G., Buesa, J. Single-chain variable fragment (scFv) antibodies against rotavirus NSP4 enterotoxin generated by phage display. Journal of Virological Methods, 121 (2): 231-238, 2004.

Monedero, V., Rodríguez-Díaz, J., Viana, R., Buesa, J., Pérez-Martínez, G. Selection of single-chain antibodies against the VP8* subunit of rotavirus VP4 outer capsid protein and their expression in Lactobacillus casei. Applied and Environmental Microbiology, 70 (11):6936-6939, 2004.

Rodríguez-Díaz, J., Montava, R., García-Díaz, A., Buesa, J. Humoral immune response to rotavirus NSP4 enterotoxin in Spanish children. Journal of Medical Virology, 77:317-322, 2005.

Javier Buesa and Jesú Rodríguez-Díaz. Molecular virology of enteric viruses (with emphasis on caliciviruses). In: Sagar M. Goyal (editor): Viruses in Foods. Food Microbiology and Food Safety Series (vol. 1). Kluwer Academic/Plenum Publishers, New York (in press).

André I., Rodríguez-Díaz, J., Buesa, J. and Zueco, J. Yeast expression of the VP8* fragment of the rotavirus VP4 spike protein and its use as immunogen in a mice model. Biotechnology and Bioengeneering (in press, 2005).

Roman E, Wilhelmi I, Colomina J, Villar J, Luz Cilleruelo M, Nebreda V, Del Alamo M, Sanchez-Fauquier A. Acute viral gastroenteritis: proportion and clinical relevance of multiple infections in Spanish children. J Med Microbiol. 2003;52:435-440.

Wilhelmi I, Roman E, Sanchez-Fauquier A. Viruses causing gastroenteritis. Clin Microbiol Infect. 2003;9:247-62.

Wilhelmi I, Mier C, Roman E, Colomina J, Prat J, Sanchez-Fauquier A. [The molecular epidemiology of the rotavirus in Spanish children. The Rotavirus Study Group (GER)] Enferm Infecc Microbiol Clin. 1999;17:509-14.

Sánchez-Fauquier A, Wilhelmi I, Colomina J, Cubero E, Roman E. Diversity of group A human rotavirus types circulating over a 4-year period in Madrid, Spain. J Clin Microbiol. 2004; 42:1609-13.

Roman Riechmann E, Wilhelmi de Cal I, Cilleruelo Pascual ML, Calvo Rey C, Garcia Garcia ML, Sanchez-Fauquier A. [Nosocomial gastroenteritis and asymptomatic rotavirus and astrovirus infection in hospitalized children] An Pediatr (Barc). 2004; 60:337-43. Spanish.

Sánchez-Fauquier A, Roman E, Colomina J, Wilhelmi I, Glass RI, Jiang B. First detection of group C rotavirus in children with acute diarrhea in Spain. Arch Virol. 2003;148:399-404

Sánchez-Fauquier A, Montero V, Moreno S, Solé M, Colomina J, Iturriza-Gomara M, Ana Revilla, Isabel Wilhelmi, Jim Gray, and Gegavi/VIGESS-Net Group. 2006. Human rotavirus G9 and G3 as major cause of diarrhea in hospitalized children, Spain. Emerg Infect Dis: http://www.cdc.gov/ncidod/EID/vol12no10/06-0384.htm

Bojsen, A., J. Buesa, R. Montava, A. S. Kvistgaard, M. B. Kongsbak, T. E. Petersen, C. W. Heegaard and J. T. Rasmussen. Inhibitory activities of bovine macromolecular whey proteins on rotavirus infections in vitro and in vivo. Journal of Dairy Science, 90: 66- 74, 2007.

Cilla G, Montes M, Gomariz M, Alkorta M, Iturzaeta A, Perez-Yarza EG, Perez-Trallero E. Rotavirus genotypes in children in the Basque Country (North of Spain): rapid and intense emergence of the G12[P8] genotype. Epidemiol Infect. 2013 Apr;141(4):868–74.

Arana A, Montes M, Jere KC, Alkorta M, Iturriza-Gómara M, Cilla G. Emergence and spread of G3P[8] rotaviruses possessing an equine-like VP7 and a DS-1-like genetic backbone in the Basque Country (North of Spain), 2015. Infect Genet Evol J Mol Epidemiol Evol Genet Infect Dis. 2016;44:137–44.

Cilla G, Montes M, Arana A. Rotavirus g12 in Spain: 2004-2006. Enferm Infecc Microbiol Clin. 2014 Jun-Jul;32(6):405. doi: 10.1016/j.eimc.2014.01.012. Epub 2014 Apr 16.

Arana A, Montes M, Jere KC, Alkorta M, Iturriza-Gómara M, Cilla G.Emergence and spread of G3P[8] rotaviruses possessing an equine-like VP7 and a DS-1-like genetic backbone in the Basque Country (North of Spain), 2015. Infect Genet Evol. 2016 Oct;44:137-144. doi: 10.1016/j.meegid.2016.06.048. Epub 2016 Jun 28.

Arana A, Jere KC, Chaguza C, Montes M, Alkorta M, Iturriza-Gómara M, Cilla G. Molecular epidemiology of G12 rotavirus strains during eight consecutive epidemic seasons in the Basque Country (North of Spain), 2010-2018. Infect Genet Evol. 2019 Mar 21;71:67-75. doi: 10.1016/j.meegid.2019.03.016.

Sweden

Johansen K, Bennet R, Bondesson K, Eriksson M, Hedlund K-O, de Verdier Klingenberg K, Uhnoo I and Svensson L. Incidence and estimate of the disease burden of rotavirus in Sweden. Acta Paediatrica 1998;Supplement.

Mirazimi A, Magnusson KE, Svensson L. A cytoplasmic region of the NSP4 enterotoxin of rotavirus is involved in retention in the endoplasmic reticulum. J Gen Virol. 200; 84:875-83.

Lundgren O, Svensson L. Pathogenesis of rotavirus diarrhea. Microbes Infect. 2001 :1145-56. Review.

Tafazoli F, Zeng CQ, Estes MK, Magnusson KE, Svensson L. NSP4 enterotoxin of rotavirus induces paracellular leakage in polarized epithelial cells. J Virol. 2001; 75:1540-6.

Johansen K, Schroder U, Svensson L. Immunogenicity and protective efficacy of a formalin-inactivated rotavirus vaccine combined with lipid adjuvants. Vaccine. 2003; 21:368-75.

United Kingdom

Flewett TH, Beards GM, Brown DW, Sanders RC. 1987. The diagnostic gap in diarrhoeal aetiology. Ciba Found Symp;128:238-49.

Brown DW, Mathan MM, Mathew M, Martin R, Beards GM, Mathan VI. 1988. Rotavirus epidemiology in Vellore, south India: group, subgroup, serotype, and electrophoretype. J Clin Microbiol 26:2410-2414.

Beards GM, Brown DW. 1988. The antigenic diversity of rotaviruses: significance to epidemiology and vaccine strategies. Eur J Epidemiol. 4:1-11.

Gray JJ, Major A, Kewley DR, Coombs RRA. (1990) Reverse passive haemagglutination with freeze-dried stabilized antibody-coupled red cells for detecting rotavirus in faecal samples. Serodiagn Immunother Infect Dis; 4: 143-149.

Ryan MJ, Ramsay M, Brown D, Gay NJ, Farrington CP, Wall PG. 1996. Hospital admissions attributable to rotavirus infection in England and Wales. J Infect Dis.;174 Suppl 1:S12-8.

Iturriza-Gómara M, Green J, Brown DWG, Desselberger U, Gray JJ. 1999. Comparison of specific and random priming in the reverse transcriptase polymerase chain reaction for genotyping group A rotaviruses. J Virol Methods. 78: 93-103.

Iturriza-Gómara M, Green J, Brown DWG, Desselberger U, Gray JJ. 2000. Diversity within the VP4 gene of rotavirus P[8] strains: Implications for RT-PCR genotyping. J Clin Microbiol. 38: 899-901.

Cubitt WD, Steele AD, Iturriza M. 2000. Characterisation of rotaviruses from children treated at a London Hospital during 1996. Emergence of strains G9P2A[6] and G3P2A[6]. J Med Virol. 61: 150-154.

Iturriza-Gómara M, Cubitt D, Steele D, Green J, Brown D, Kang G, Desselberger U, Gray J 2000. Characterisation of rotavirus G9 strains isolated in the UK between 1995 and 1998. J Med Virol: 61: 510-517.

Iturriza-Gómara M, Green J, Brown D, Ramsay M, Desselberger U, Gray JJ. 2000. Molecular epidemiology of human rotavirus infections in the UK between 1995 and 1998. J Clin Microbiol: 38: 4094-4401.

Iturriza-Gómara M, Green J, Gray JJ. 2000. Methods of rotavirus detection, sero-and genotyping, sequencing and phylogenetic analysis. (Chapter 10; pp189-217) in Rotaviruses: Methods and Protocols. Methods in Molecular Medicine. Edited by J.J. Gray and U. Desselberger. Humana Press, Totowa, NJ, USA.

Gray JJ and Desselberger U. (2000) Ed. Rotaviruses: Methods and Protocols, Methods in Molecular Medicine. Humana Press, Totowa, NJ, USA.

Iturriza-Gómara M. 2000. Molecular epidemiology of rotavirus infections in the UK. PhD thesis.

Iturriza-Gómara M, Isherwood B, Desselberger U, Gray J. 2001. Reassortment in vivo: a driving force for diversity of human rotavirus strains isolated in the UK between 1995 and 1999. J Virol. 75: 3696-3705.

Kang G, Raman T, Green J, Gallimore CI, Brown DW. 2001. Distribution of rotavirus G and P types in north and south Indian children with acute diarrhoea in 1998-99.Trans R Soc Trop Med Hyg 95:491-2.

Asmah R, Green J, Armah GR, Gallimore CI, Gray JJ, Iturriza-Gómara M, Anto F, Oduro A, Binka FN, Brown DWG, Cutts F. 2001. Rotavirus G and P types in rural Ghana. J Clin Microbiol: 39: 1981-1984.

Iturriza-Gómara M, Cubitt D, Desselberger U, Gray, J. 2001.An amino acid substitution at the antigenic region A of the VP7 protein of G2 rotavirus strain associated with the failure to serotype. J Clin Microbiol. 39: 3796-3798.

Desselberger U, Gray J. (2001). Viral gastroenteritis. In: Medicine Eds G Griffin and T Harrison. The Medicine Publishing Company Ltd, Oxford, pp 68-71.

Kang G, Green J, Gallimore CI, Brown DW. 2002. Molecular epidemiology of rotaviral infection in South Indian children with acute diarrhea from 1995-1996 to 1998-1999. J Med Virol. May;67:101-5.

El-Attar L, Dhaliwal W, Iturriza-Gómara M, Bridger JC. 2002. Identification and molecular characterisation of a bovine G3 rotavirus which causes age-independent diarrhoea in cattle. J Clin Microbiol. 40:937-42.

Ciarlet M, Ludert JM, Iturriza-Gómara M, Liprandi F, Gray JJ, Desselberger U, Estes MK. 2002. The initial interaction of rotavirus strains with N-acetyl-neuraminic (sialic) acid residues on the cell surface correlates with VP4 genotype, not species of origin. J Virol. 76: 4087-95.

Iturriza-Gómara M, Wong C, Blome S, Desselberger U, Gray J. 2002. Molecular Characterisation of VP6 Genes of Human Rotavirus Isolates: Correlation of Genogroups with Subgroups and Evidence of Independent Segregation. J Virol.76: 6596-601.

Iturriza-Gómara M, Blome S, Desselberger U, Gray J. 2002. Rotavirus Subgroup Characterisation by Restriction Endonuclease Digestion of a cDNA Fragment of the VP6 Gene. J Virol Methods. 105:99-103.

Iturriza-Gómara M, Auchterlonie IA, Zaw W, Molyneaux P, Desselberger U, Gray J. 2002. Rotavirus gastroenteritis and CNS infection: detection and characterisation of the VP7 and VP4 genes of rotavirus strains isolated from paired faecal and CSF samples from a child with CNS symptoms. J Clin Microbiol. 40:4797-4799.

Simpson R, Aliyu S, Iturriza-Gómara M, Desselberger U, Gray J. 2003. Infantile viral gastroenteritis: on the way to closing the diagnostic gap. J Med Virol.70: 258-262.

The Navrongo Rotavirus Research Group. 2003. Incidence and Risk Factors of Paediatric Rotavirus Diarrhoea in Northern Ghana. Trop Med Int Health. 8:840-846.

Iturriza-Gómara M, Desselberger U, Gray JJ. 2003. Molecular epidemiology of rotaviruses: Genetic Mechanisms Associated with Diversity. In Viral Gastroenteritis. Prespectives in Medical Virology. Desselberger U & Gray JJ (Eds). Elsevier.

Binka, F. N., Anto, F. K., Oduro, A. R., Awini, E. A., Nazzar, A. K., Armah,G. E., Asmah, R. H., Hall, A. J., Cutts, F., Alexander, N., Brown, D., Green, J., Gray, J. and Iturriza-Gomara, M. 2003. Incidence and risk factors of paediatric rotavirus diarrhoea in northern Ghana. Trop Med Int Health 8: 840-846.

Desselberger U, Gray J (Eds). 2003. Viral gastroenteritis. Perspectives in Medical Virology, 9. Elsevier.

Iturriza-Gómara M, Anderton E, Kang G, Gallimore C, Phillips W, Desselberger U, Gray J. 2003. Evidence for Genetic Linkage Between the Gene Segments Encoding NSP4 and VP6 Proteins in Common and Reassortant Human Rotavirus Strains. J Clin Microbiol, 41, 3566-3573.

Kang G, Iturriza-Gómara M, Wheeler JG, Crystal P, Monica B, Moses PD, Gallimore C, Brown D and Gray J. 2004. Quantitation of Group A rotavirus RNA by real time reverse-transcription polymerase chain reaction: Correlation with clinical severity in children in South India. J Med Virol. 73:118-122.

Iturriza-Gómara M, Kang G, Mammen A, Jana AK, Abraham M, Desselberger U, Brown D and Gray J. 2004. Characterisation of G10P[11] Rotaviruses Causing Acute Gastroenteritis in Neonates and Infants in Vellore, India. J Clin Microbiol. 42: 2541-2547.

Iturriza-Gómara M, Clarke I, Desselberger U, Brown D, Thomas D, Gray J. 2004. Seroepidemiology of Group C Rotavirus Infection in England and Wales. Eur J Epidemiol. 19: 589-595.

Cook N, Bridger J, Kendal K, Iturriza-Gómara M, Gray J. 2004. The zoonotic potential of rotavirus. Journal of Infection.48: 289-302.

Iturriza-Gómara M, Kang G, Gray J. Rotavirus Genotyping: Keeping up with an evolving population of human rotaviruses. J Clin Virol. 2004. 31;259-265.

Desselberger U, Gray J. 2004. Viruses associated with acute diarrhoeal disease. In: Principles and Practice of Clinical Virology, Eds Zuckerman, AJ, Banatvala JE, Pattison JR, Griffiths PD, Schoub BD. John Wiley and Sons, Ltd, Chichester.

Desselberger U, Gray J. 2005. Viral gastroenteritis. In: Medicine Eds G Griffin and T Harrison. The Medicine Publishing Company Ltd, Oxford, pp 78-80.

Cataloluk O, Iturriza M, Gray J. 2005 Molecular characterization of rotaviruses circulating in the population inTurkey. Epidemiol Infect. 133:673-8.

Amar CF, East CL, Grant KA, Gray J, Iturriza-Gómara M, Maclure EA, McLauchlin J. 2005 Detection of viral, bacterial, and parasitological RNA or DNA of nine intestinal pathogens in fecal samples archived as part of the English infectious intestinal disease study: assessment of the stability of target nucleic acid. Diagn Mol Pathol. 14:90-6.

Arista S, Giammanco GM, De Grazia S, Colomba C, Martella V, Cascio A, Iturriza-Gómara M. G2 rotavirus infections in an infantile population of the South of Italy: Variability of viral strains over time. J Med Virol. 2005; 77(4):587-94.

Martella V, Banyai K, Ciarlet M, Iturriza-Gómara M, Lorusso E, De Grazia S, Arista S, Decaro N, Elia G, Cavalli A, Corrente M, Lavazza A, Baselga R, Buonavoglia C. Relationships among porcine and human P[6] rotaviruses: Evidence that the different human P[6] lineages have originated from multiple interspecies transmission events. Virology. 2005.

Banerjee I, Ramani S, Primrose B, Moses P, Iturriza-Gómara M, Gray JJ, Jaffar S, Monica B, Muliyil JP, Brown DW, Estes MK, Kang G. 2006. Comparative study of the epidemiology of rotavirus in children from a community-based birth cohort and a hospital in South India. J Clin Microbiol 44: 2468-74.

Sánchez-Fauquier A, Montero V, Moreno S, Solé M, Colomina J, Iturriza-Gómara M, Ana Revilla, Isabel Wilhelmi, Jim Gray, and Gegavi/VIGESS-Net Group. 2006. Human rotavirus G9 and G3 as major cause of diarrhea in hospitalized children, Spain. Emerg Infect Dis:

Farahtaj F, Gallimore CI, Iturriza-Gómara M, Taremi M, Zali MR, Edalatkhah H, Fayaz A, Gray JJ. 2006. Rotavirus VP7, VP4 and VP6 genotypes co-circulating in Tehran, Iran, between 2003 and 2004. Epidemiol Infect. 2006 Nov 17:1-5

Banerjee I, Gladstone BP, Le Fevre AM, Ramani S, Iturriza-Gómara M, Gray JJ, Brown DW, Estes MK, Muliyil JP, Jaffar S, Kang G.2007. Neonatal Infection with G10P[11] Rotavirus Did Not Confer Protection against Subsequent Rotavirus Infection in a Community Cohort in Vellore, South India. J Infect Dis. 195(5):625-32

Ramani S, Banerjee I, Gladstone BP, Sarkar R, Selvapandian D, Le Fevre AM, Jaffar S, Iturriza-Gomara M, Gray JJ, Estes MK, Brown DW, Kang G. 2007 Geographic information systems and genotyping in the identification of rotavirus G12 infections in an urban slum with subsequent detection in hospitalized children: Emergence of G12 genotype in south India. J Clin Micobiol45(2):432-7,

Iturriza Gomara M, Gallimore CI, Gray J. 2007. Gastroenteric Viruses. in Foodborne Diseases, Ed Simjee S. Humana Press, New Jersey. 213-230, in press.

Mustafizur Rahman, Jelle Matthijnssens, Xuelei Yang, Thomas Delbeke, Ingrid Arijs, Koki Taniguchi, Miren Iturriza-Gomara, Nadia Iftekharuddin, Tasnim Azim, and Marc Van Ranst 2007. Evolutionary history and global spread of the emerging G12 human rotaviruses J. Virol. 81: 2382-2390.

Iturriza Gómara M, Simpson R., Perault A.M. , Redpath C., Lorgelly P., Joshi D., Mugford M., Hughes C.A., Dalrymple J., Desselberger U., Gray J. 2007. Structured surveillance of infantile gastroenteritis in East Anglia, UK: incidence of infection with common viral gastroenteric pathogens. Epidemiol & Infect: EPub ahead of print.

Lorgelly PK, Joshi D, Iturriza Gómara M, Flood C, Hughes CA, Dalrymple J,Gray J, Mugford M. 2007. Infantile gastroenteritis in the community: a cost-of-illness study.Epidemiol Infect. EPub ahead of print.

Lorgelly PK, Joshi D, Iturriza Gómara M, Gray J, Mugford M. Exploring the cost effectiveness of an immunization programme for rotavirus gastroenteritis in the United Kingdom. 2007. EPub ahead of print.

Monica B, Ramani S, Banerjee I, Primrose B, Iturriza-Gómara M, Gallimore CI, Brown DW, M F, Moses PD, Gray JJ, Kang G.2007. Human caliciviruses in symptomatic and asymptomatic infections in children in Vellore, South India. J Med Virol. 79(5):544-51.

Amar CF, East CL, Gray J, Iturriza-Gómara M, Maclure EA, McLauchlin J. Detection by PCR of eight groups of enteric pathogens in 4,627 faecal samples: re-examination of the English case-control Infectious Intestinal Disease Study(1993-1996).2007. Eur J Clin Microbiol Infect Dis May;26(5):311-23.

Gladstone BP, Iturriza-Gómara M, Ramani S, Monica B, Banerjee I, Brown DW, Gray JJ, Muliyil J, Kang G. 2007. Polymerase chain reaction in the detection of an ‘outbreak’ of asymptomatic viral infections in a community birth cohort in south India. Epidemiol Infect. 24;1-7.

Banerjee I, Ramani S, Primrose B, Iturriza-Gómara M, Gray JJ, Brown DW, Kang G. 2007 Modification of rotavirus multiplex RT-PCR for the detection of G12 strains based on characterization of emerging G12 rotavirus strains from South India. J. Med. Virol. Sep;79(9):1413-21.

Banerjee I, Gladstone BP, Le Fevre AM, Ramani S, Iturriza-Gómara M, Gray JJ, Brown DW, Estes MK, Muliyil JP, Jaffar S, Kang G.2007. Neonatal Infection with G10P[11] Rotavirus Did Not Confer Protection against Subsequent Rotavirus Infection in a Community Cohort in Vellore, South India. J Infect Dis. 195(5):625-32

Ramani S, Banerjee I, Gladstone BP, Sarkar R, Selvapandian D, Le Fevre AM, Jaffar S, Iturriza-Gómara M, Gray JJ, Estes MK, Brown DW, Kang G. 2007 Geographic information systems and genotyping in the identification of rotavirus G12 infections in an urban slum with subsequent detection in hospitalized children: Emergence of G12 genotype in south India. J Clin Micobiol45(2):432-7.

Iturriza Gómara M, Gallimore CI, Gray J. 2007. Gastroenteric Viruses. in Foodborne Diseases, Ed S. Simjee. Humana Press, New Jersey. pp 215-232.

Mustafizur Rahman, Jelle Matthijnssens, Xuelei Yang, Thomas Delbeke, Ingrid Arijs, Koki Taniguchi, Miren Iturriza-Gómara, Nadia Iftekharuddin, Tasnim Azim, and Marc Van Ranst 2007. Evolutionary history and global spread of the emerging G12 human rotaviruses J. Virol. 81: 2382-2390.

Amar CF, East CL, Gray J, Iturriza-Gómara M, Maclure EA, McLauchlin J. Detection by PCR of eight groups of enteric pathogens in 4,627 faecal samples: re-examination of the English case-control Infectious Intestinal Disease Study(1993-1996).2007. Eur J Clin Microbiol Infect Dis May;26(5):311-23.

Gladstone BP, Iturriza-Gómara M, Ramani S, Monica B, Banerjee I, Brown DW, Gray JJ, Muliyil J, Kang G. 2007. Polymerase chain reaction in the detection of an ‘outbreak’ of asymptomatic viral infections in a community birth cohort in south India. Epidemiol Infect. 24;1-7.

Banerjee I, Ramani S, Primrose B, Iturriza-Gómara M, Gray JJ, Brown DW, Kang G. 2007. Modification of rotavirus multiplex RT-PCR for the detection of G12 strains based on characterization of emerging G12 rotavirus strains from South India. J. Med. Virol. Sep;79(9):1413-21.

Rodrigues F, Iturriza M, Gray J, Januário L, Lemos L. 2007. Epidemiology of rotavirus in Portugal: G9 as a major cause of diarrhoea in non-hospitalised children. J Clin Virol. Sep 15; [Epub ahead of print].

Banerjee I, Iturriza-Gómara M, Rajendran P, Primrose B, Ramani S, Gray JJ, Brown DW, Kang G.2007. Molecular characterization of G11P[25] and G3P[3] human rotavirus strains associated with asymptomatic infection in South India. J Med Virol. Nov;79(11):1768-74.

Iturriza Gómara M, Simpson R., Perault A.M. , Redpath C., Lorgelly P., Joshi D., Mugford M., Hughes C.A., Dalrymple J., Desselberger U., Gray J. 2008. Structured surveillance of infantile gastroenteritis in East Anglia, UK: incidence of infection with common viral gastroenteric pathogens. Epidemiol & Infect: 136(1):23-33.

Lorgelly PK, Joshi D, Iturriza Gómara M, Flood C, Hughes CA, Dalrymple J,Gray J, Mugford M. 2008. Infantile gastroenteritis in the community: a cost-of-illness study. Epidemiol Infect. 136(1):34-43

Lorgelly PK, Joshi D, Iturriza Gómara M, Gray J, Mugford M. 2008. Exploring the cost effectiveness of an immunization programme for rotavirus gastroenteritis in the United Kingdom. Epidemiol Infect. 136(1):44-55

Iturriza-Gómara M, Dallman T, Bányai K, Böttiger B, Buesa J, Diedrich S, Fiore L, Johansen K, Korsun N, Kroneman A, Lappalainen M, László B, Maunula L, Matthinjnssens J, Midgley S, Mladenova Z, Poljsak-Prijatelj M, Pothier P, Ruggeri FM, Sanchez-Fauquier A, Schreier E, Steyer A, Sidaraviciute I, Tran AN, Usonis V, Van Ranst M, de Rougemont A, Gray J. Rotavirus surveillance in europe, 2005-2008: web-enabled reporting and real-time analysis of genotyping and epidemiological data. J Infect Dis. 2009 Nov 1;200 Suppl 1:S215-21. doi: 10.1086/605049.

Aladin F, Nawaz S, Iturriza-Gómara M, Gray J. Identification of G8 rotavirus strains determined as G12 by rotavirus genotyping PCR: updating the current genotyping methods. J Clin Virol. 2010 Apr;47(4):340-4. doi: 10.1016/j.jcv.2010.01.004. Epub 2010 Feb 6.

turriza-Gómara M, Dallman T, Bányai K, Böttiger B, Buesa J, Diedrich S, Fiore L, Johansen K, Koopmans M, Korsun N, Koukou D, Kroneman A, László B, Lappalainen M, Maunula L, Marques AM, Matthijnssens J, Midgley S, Mladenova Z, Nawaz S, Poljsak-Prijatelj M, Pothier P, Ruggeri FM, Sanchez-Fauquier A, Steyer A, Sidaraviciute-Ivaskeviciene I, Syriopoulou V, Tran AN, Usonis V, VAN Ranst M, DE Rougemont A, Gray J. Rotavirus genotypes co-circulating in Europe between 2006 and 2009 as determined by EuroRotaNet, a pan-European collaborative strain surveillance network. Epidemiol Infect. 2011 Jun;139(6):895-909. doi: 10.1017/S0950268810001810. Epub 2010 Aug 16.

Hungerford D, Vivancos R; EuroRotaNet network members, Read JM, Pitzer VE, Cunliffe N, French N, Iturriza-Gómara M. In-season and out-of-season variation of rotavirus genotype distribution and age of infection across 12 European countries before the introduction of routine vaccination, 2007/08 to 2012/13. Euro Surveill. 2016;21(2). doi: 10.2807/1560-7917.ES.2016.21.2.30106.

Mukhopadhya I, Murdoch H, Berry S, Hunt A, Iturriza-Gomara M, Smith-Palmer A, Cameron JC, Hold GL. Changing molecular epidemiology of rotavirus infection after introduction of monovalent rotavirus vaccination in Scotland. Vaccine. 2017 Jan 3;35(1):156-163. doi: 10.1016/j.vaccine.2016.11.028. Epub 2016 Nov 18.

Hungerford D, Allen DJ, Nawaz S, Collins S, Ladhani S, Vivancos R, Iturriza-Gómara M. Impact of rotavirus vaccination on rotavirus genotype distribution and diversity in England, September 2006 to August 2016. Euro Surveill. 2019 Feb;24(6). doi: 10.2807/1560-7917.ES.2019.24.6.1700774.